Tridimensional Diagnostic Framework for Neurodegenerative Diseases
Neurodiagnoses unifies multi-omics data, genetics, and neuroimaging in a single integrated platform. From Parkinson's to Alzheimer's, from ALS to Huntington's — analyze complex CNS disorders with scientifically validated methods and reproducible experiments.
The Tridimensional Approach
Analyze any neurodegenerative disease across three fundamental axes to build a complete mechanistic picture: from genetic predisposition to molecular pathology to structural consequences.
Axis 1: Etiology
Etiological factors including genetic risk, environmental influences, and disease predisposition. Genetics is a crucial component, but not the only one.
Examples: APOE, LRRK2, TREM2, GBA, MAPT, HTT, environmental factors
Axis 2: Markers
Molecular biomarkers from multi-omics data: proteomics, transcriptomics, metabolomics. The mechanistic layer.
Examples: CSF biomarkers, tissue proteomics, RNA-seq, metabolic profiles
Axis 3: Anatomic-Clinic Phenotype
Neuroimaging, brain structure, clinical manifestations. The anatomical and clinical phenotypic layer.
Examples: MRI volumetry, PET imaging, DTI, functional connectivity, clinical symptoms
Unified Scientific Validation
Neurodiagnoses ensures scientific congruence across all analysis workflows. Whether you're analyzing an individual patient or a research cohort, the underlying validated methodology remains consistent, preventing logic divergence for any disease.
Validated Results
62.5% causal validation, 37.5% spatial validation
Consistent Methodology
Same science across all tools and workflows
Reproducible Experiments
Run complex scientific analyses with one click
Applicable to Any Neurodegenerative Disease
The tridimensional framework is disease-agnostic. Whether you're studying Alzheimer's, Parkinson's, ALS, Huntington's, or any complex CNS disorder, Neurodiagnoses provides the same rigorous multi-axis analysis.
Alzheimer's Disease
APOE → Aβ/tau → Hippocampal atrophy
Parkinson's Disease
LRRK2/GBA → α-synuclein → Substantia nigra
Huntington's Disease
HTT CAG → mHTT → Striatal degeneration
ALS / FTD
C9orf72 → TDP-43 → Motor cortex / frontal
Smart Navigation: We Guide You to the Right Tool
Our Onboarding Wizard asks 3 questions and routes you to the perfect analysis workflow — regardless of which disease you're studying.
Step 1: Profile
Are you a clinician, researcher, or data scientist?
Step 2: Objective
Do you need individual diagnosis or cohort validation?
Step 3: Data
What data do you have? Genetics, proteomics, imaging?
Result: Automatic redirection to:
Start Analyzing Complex CNS Disorders Today
Join researchers worldwide using Neurodiagnoses for validated, transparent, multi-axis analysis of neurodegenerative diseases.
⚠️ For research purposes only - Not a validated clinical diagnostic tool
Platform validated with Alzheimer's disease cohorts (0.0% deviation vs traditional methods). Framework applicable to any neurodegenerative disorder.