Step 1: Patient Demographics & Clinical Assessment

Patient ID (Anonymized)

Age at Onset

Sex at Birth

Primary Clinical Phenotype

Cognitive Impairment Movement Disorder Motor Neuron Signs Cerebellar Ataxia

Step 2: Core Biomarkers & Genetic Profile

Aβ42/40 Ratio

p-tau181 (pg/mL)

NfL (pg/mL)

α-syn RT-QuIC

APOE Genotype

Known Pathogenic Variants

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