The Neurodiagnoses Ecosystem
An AI-powered, open-source platform designed to integrate multi-modal data and enhance the diagnostic precision, risk assessment, and prognostic understanding of complex neurodegenerative diseases (NDDs).
A Tridimensional Diagnostic Framework
Our system moves beyond static labels by organizing all patient data along three fundamental axes, providing a holistic and mechanistic view of the disease.
Axis 1: Etiology (The Why)
Focuses on the root cause or predisposition, including genetic factors (monogenic or risk alleles) and significant environmental or infectious contributors.
Axis 2: Molecular Pathology (The Plot)
Describes the underlying biological processes, integrating multi-omics data to profile active pathological pathways like amyloid, tau, and neuroinflammation.
Axis 3: Phenotype (The How & Where)
Captures the observable manifestation, correlating clinical symptoms with their neuroanatomical findings from imaging.
The Dual-Output Engine
The Bayesian inference engine generates a comprehensive "Neurodegenerative Signature" for each patient, composed of two key parts:
1. Classical Differential Diagnosis
A familiar, ranked list of classical neurodegenerative diseases, each with a calculated posterior probability, enabling direct clinical interpretation.
2. Tridimensional Annotation
A rich, structured report detailing the patient's unique profile across the three axes, providing deep insight into the specific mechanisms at play for precision medicine.